B Dean Selected Research

Pirenzepine

11/2009	Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia.
12/2006	[3H]Pirenzepine binding in the pathology of schizophrenia: studies in Brodmann's area 6.
1/2002	Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia.
6/2001	Low muscarinic receptor binding in prefrontal cortex from subjects with schizophrenia: a study of Brodmann's areas 8, 9, 10, and 46 and the effects of neuroleptic drug treatment.
9/2000	Decreased muscarinic receptor binding in subjects with schizophrenia: a study of the human hippocampal formation.
3/2000	Muscarinic1 and 2 receptor mRNA in the human caudate-putamen: no change in m1 mRNA in schizophrenia.

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B Dean Research Topics

Disease

43	Schizophrenia (Dementia Praecox) 01/2018 - 01/2000
12	Bipolar Disorder (Manic Depressive Psychosis) 01/2017 - 10/2001
9	Mental Disorders (Mental Disorder) 01/2018 - 03/2001
5	Major Depressive Disorder (Major Depressive Disorders) 01/2017 - 08/2009
3	Mood Disorders (Mood Disorder) 08/2015 - 07/2013
2	Inflammation (Inflammations) 11/2016 - 01/2011
1	Wounds and Injuries (Trauma) 01/2018
1	Foreign Bodies (Foreign Body) 01/2018
1	Venous Thromboembolism 05/2010
1	Psychotic Disorders (Schizoaffective Disorder) 04/2010
1	Alzheimer Disease (Alzheimer's Disease) 01/2002

Drug/Important Bio-Agent (IBA)

12	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2018 - 09/2000
11	Cholinergic Agents (Cholinergics)IBA 01/2015 - 08/2000
9	Messenger RNA (mRNA)IBA 01/2018 - 03/2000
8	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2000
6	Dopamine (Intropin)FDA LinkGeneric 01/2012 - 01/2001
6	PirenzepineIBA 11/2009 - 03/2000
3	Muscarinic M1 ReceptorIBA 01/2018 - 06/2012
3	Protein Isoforms (Isoforms)IBA 01/2017 - 01/2002
3	EnzymesIBA 11/2016 - 02/2003
3	Biomarkers (Surrogate Marker)IBA 01/2016 - 11/2009
3	gamma-Aminobutyric Acid (GABA)IBA 01/2016 - 01/2001
3	Pharmaceutical PreparationsIBA 08/2015 - 11/2009
3	Acetylcholine (Acetylcholine Chloride)FDA Link 04/2010 - 01/2001
3	Neurotransmitter Agents (Neurotransmitter)IBA 03/2007 - 03/2002
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 08/2003 - 07/2000
3	GABA-A Receptors (GABA(A) Receptor)IBA 10/2001 - 01/2001
2	Phospholipase C betaIBA 01/2017 - 07/2008
2	MicroRNAs (MicroRNA)IBA 01/2016 - 02/2013
2	Nitric Oxide Synthase (NO Synthase)IBA 01/2016 - 10/2001
2	Glutamic Acid (Glutamate)FDA Link 01/2016 - 07/2008
2	Antipsychotic Agents (Antipsychotics)IBA 06/2012 - 06/2001
2	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 01/2012 - 07/2000
2	LigandsIBA 01/2012 - 07/2000
2	Cholinergic ReceptorsIBA 04/2010 - 09/2000
2	Biological ProductsIBA 11/2009 - 07/2000
2	AFDX 384IBA 08/2009 - 03/2000
2	ApolipoproteinsIBA 12/2006 - 01/2002
2	AMPA Receptors (AMPA Receptor)IBA 08/2003 - 07/2000
2	N-Methylaspartate (NMDA)IBA 08/2003 - 07/2000
2	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 08/2003 - 07/2000
2	Kainic Acid (Kainate)IBA 08/2003 - 07/2000
2	Ionotropic Glutamate ReceptorsIBA 08/2003 - 07/2000
2	Apolipoproteins D (Apo D)IBA 02/2003 - 03/2001
2	Serotonin (5 Hydroxytryptamine)IBA 01/2001 - 01/2001
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2017
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2017
1	Lactic Acid (Lactate)FDA LinkGeneric 11/2016
1	Glucose (Dextrose)FDA LinkGeneric 11/2016
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 11/2016
1	Pyruvic Acid (Pyruvate)IBA 11/2016
1	Oxidoreductases (Dehydrogenase)IBA 11/2016
1	Interleukin-6 (Interleukin 6)IBA 11/2016
1	Arginine (L-Arginine)FDA Link 01/2016
1	AgmatineIBA 01/2016
1	Amino Acids FDA Link 01/2016
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2016
1	ArginaseIBA 01/2016
1	CitrullineIBA 01/2016
1	OrnithineIBA 01/2016
1	Selenium-Binding ProteinsIBA 08/2015
1	Beclin-1IBA 02/2015
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 07/2013
1	Type I Tumor Necrosis Factor ReceptorsIBA 07/2013
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2013
1	InterleukinsIBA 07/2013
1	Type II Tumor Necrosis Factor ReceptorsIBA 07/2013
1	butyl phosphorotrithioate (DEF)IBA 02/2013
1	Muscarinic M4 ReceptorIBA 06/2012
1	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 01/2012
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2012
1	Histone Deacetylase InhibitorsIBA 12/2011
1	Histone Deacetylases (Histone Deacetylase)IBA 12/2011
1	Histones (Histone)IBA 12/2011
1	ChromatinIBA 12/2011
1	Nerve Growth Factors (Neurotrophins)IBA 01/2011
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 04/2010
1	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 07/2009
1	Serotonin ReceptorsIBA 07/2008
1	Clozapine (Clozaril)FDA LinkGeneric 07/2008
1	mu Opioid Receptors (mu Opioid Receptor)IBA 12/2006
1	SynaptophysinIBA 04/2006
1	Qa-SNARE Proteins (Syntaxin)IBA 04/2006
1	Cell Adhesion MoleculesIBA 04/2006
1	R-SNARE Proteins (Vesicle-Associated Membrane Protein)IBA 04/2006
1	Dynamin IIBA 04/2006
1	alpha-SynucleinIBA 04/2006
1	iodosulprideIBA 05/2004
1	SpiperoneIBA 05/2004
1	Haloperidol (Haldol)FDA LinkGeneric 05/2004
1	Dizocilpine Maleate (Dizocilpine)IBA 08/2003
1	Ion Channels (Ion Channel)IBA 08/2003
1	ImmunosorbentsIBA 02/2003
1	Phorbol EstersIBA 01/2002
1	Protein Kinase CIBA 01/2002
1	Phorbol 12,13-DibutyrateIBA 01/2002

Therapy/Procedure

2	Therapeutics 01/2016 - 05/2001
1	Critical Care (Surgical Intensive Care) 01/2018
1	Thoracotomy 01/2018
1	Arthroplasty 05/2010